Why the study?
Variation in resting metabolic rate may be linked to health-related factors, but whether intra-assessment variability differs by sex and relates similarly to health factors is unclear.
Is intra-assessment resting metabolic rate variability similar in men and women, and is it associated with cardiometabolic health-related factors?
Is intra-assessment resting metabolic rate variability similar in men and women, and is it associated with cardiometabolic health-related factors?
Intra-assessment resting metabolic rate variability is higher in men than women, and the coefficient of variation for respiratory exchange ratio may serve as a potential marker of cardiometabolic risk in young men.
Men exhibit higher RMR variability than women, with RER CV linked to HRV only in men; observational findings leave open its cardiometabolic marker potential.
In humans, the variation in resting metabolic rate (RMR) might be associated with health-related factors, as suggested by previous studies. This study explored whether the intra-assessment RMR variability (expressed as a coefficient of variation (CV; %)) is similar in men and women and if it is similarly associated with diverse health-related factors. The RMR of 107 young, and relatively healthy adults, was assessed using indirect calorimetry. Then, the CV for volumes of oxygen consumption (VO2) and carbon dioxide production (VCO2), respiratory exchange ratio (RER), and resting energy expenditure (REE) were computed as indicators of intra-assessment RMR variability. Body composition, cardiorespiratory fitness (peak VO2 uptake), circulating cardiometabolic risk factors, and heart rate and its variability (HR and HRV) were assessed. Men presented higher CVs for VO2, VCO2, and REE (all p ≤ 0.001) compared to women. Furthermore, in men, the intra-assessment RER variability was associated with vagal-related HRV parameters and with mean HR (standardized β = −0.36, −0.38, and 0.41, respectively; all p < 0.04). In contrast, no associations were observed in women. In conclusion, men exhibited higher variability (CVs for VO2, VCO2, and REE) compared to women. The CV for RER could be a potential marker of cardiometabolic risk in young men.
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Alcántara et al. (2022) studied this question.
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