The slime-producing microorganism A. viscosus Ny1 was tested on its plaque-forming ability and its cariogenicity in rats fed on glucose or sucrose diets. In mono-associated as well as SPF O-M rats, strain Ny1 caused considerable plaque formation on both diets. The role of the resident microflora on the establishment of strain Nyl was investigated by varying its composition with antibiotics. It was found that pre-experimental treatment with erythromycin prevented the establishment of strain Ny1 in SPF rats. In mono-associated rats, strain Ny1 caused no smooth surface caries and little fissure caries. However, in SPF rats, the interaction of strain Ny1 with the resident microflora resulted in considerable smooth surface and fissure caries on both diets. Smooth surface caries was greater on the sucrose diet.
No takes yet. Share an insight, caveat, or question.
Hoeven et al. (2009) studied this question.