A sticky end: A heterotropic conjugate of actin and myosin–actomysin–is stabilized by a water-soluble dendritic “molecular glue” bearing nine pendant guanidinium ions (see picture; ATP= adenosine triphosphate, ADP=adenosine diphosphate). The ATP-driven sliding motion of actin filaments on a myosin-functionalized coverslip is decelerated or totally arrested with a higher-generation dendrimer, but not with a lower-generation one.
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Okuro et al. (2010) studied this question.
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