June 1, 1992VirologyOpen Access

Molecular cloning, sequence analysis, in vitro expression, and immunoprecipitation of the major inner capsid protein of the IDIR strain of group B rotavirus (GBR)

View Full Paper

Ask AI

Bookmark

Population

Infectious diarrhea of infant rats strain of group B rotavirus RNA purified from infected rat feces

Comparison

Molecular cloning, sequence analysis, in vitro… vs Group A rotaviruses and the human ADRV strain of…

Design

Preclinical

Authors

Discussion

Hypothesis-generating for group B rotavirus immunoassay reagents; leaves open human validation before any diagnostic use.

Population

Infectious diarrhea of infant rats (IDIR) strain of group B rotavirus (GBR) RNA purified from infected rat feces

Intervention

Molecular cloning, sequence analysis, in vitro expression, and immunoprecipitation of gene 6

Comparator

Group A rotaviruses (GAR) and the human ADRV strain of GBR

Outcome

Sequence conservation, hydrophilicity, and immunoprecipitation reactivity of the major inner capsid proteinsurrogate

The IDIR gene 6 product displays group-specific epitopes and may be useful as a standard reagent in immunoassays for detecting group B rotavirus.

Eiden et al. (1992) studied this question.

View Full Paper

Ask AI

Bookmark