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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnzyme RedesignTrevor M. Penning and Joseph M. JezView Author Information Department of Pharmacology, University of Pennsylvania School of Medicine, 135 John Morgan Building, 3620 Hamilton Walk, Philadelphia, Pennsylvania 19104-6084 Structural Biology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037 Cite this: Chem. Rev. 2001, 101, 10, 3027–3046Publication Date (Web):September 1, 2001Publication History Received16 March 2001Published online1 September 2001Published inissue 1 October 2001https://pubs.acs.org/doi/10.1021/cr000049nhttps://doi.org/10.1021/cr000049nresearch-articleACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views2123Altmetric-Citations124LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstract
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Penning et al. (2001) studied this question.
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