Why the study?
The study aimed to assess the global oxidant and antioxidant status in infants born to preeclamptic mothers and evaluate their correlation with cardiac functions.
Does maternal preeclampsia alter oxidative stress and cardiac function in infants?
Does maternal preeclampsia alter oxidative stress and cardiac function in infants?
While maternal preeclampsia increases oxidative stress in infants, it does not appear to acutely affect echocardiographic parameters of cardiac function.
Answers are grounded in this paper and cite their sources.
Oxidative status may correlate with neonatal cardiac changes after preeclampsia; leaves open whether targeted interventions improve outcomes.
OBJECTIVE: The present study aimed to assess the global oxidant and antioxidant status in infants born to preeclamptic mothers and their correlation with cardiac functions. STUDY DESIGN: We compared 40 infants born to preeclamptic mothers with 40 premature infants born to normotensive mothers. We assessed the relationship between echocardiographic measurements and total antioxidant capacity (TAC) and total oxidant status (TOS) values. RESULTS: = 0.03, 0.04, and 0.039, respectively) than in the control group. We did not observe any correlation between echocardiographic measurements and TAC, TOS, and OSI levels in infants born to preeclamptic mothers. CONCLUSION: Compared with the control group, despite higher TAC levels in infants born to preeclamptic mothers, concurrent elevated OSI levels reveal that the oxidant-antioxidant balance is disturbed in favor of oxidants. Furthermore, the findings of this study suggest that echocardiographic parameters are unaffected by the oxidant status.
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Arman et al. (2018) studied this question.
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