Population
Human plasma and purified human antithrombin III (in vitro model)
Comparison
Unfractionated heparin, low molecular weight… vs Same heparin preparations in the absence of…
Design
Preclinical
Authors
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Calcium may affect heparin activity assays; leaves open relevance to human dosing or outcomes.
Calcium alters the anti-factor Xa to anti-thrombin activity ratios of unfractionated heparin to approximate those of low molecular weight heparins in human plasma.
Schoen et al. (1992) studied this question.
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