Why the study?
AF is an increasingly burdensome arrhythmia linked to higher stroke incidence, prompting the need to assess thrombogenesis risk in persistent nonvalvular AF using echocardiographic modalities in relation to CHA2DS2-VASc score.
Do echocardiographic parameters of the left atrial appendage correlate with the CHA2DS2-VASc score in patients with persistent nonvalvular atrial fibrillation?
Do echocardiographic parameters of the left atrial appendage correlate with the CHA2DS2-VASc score in patients with persistent nonvalvular atrial fibrillation?
Echocardiographic parameters of left atrial appendage function correlate with the CHA2DS2-VASc score, supporting its use for assessing stroke risk and thrombogenicity in nonvalvular AF.
Answers are grounded in this paper and cite their sources.
May support integrating LAA echo velocities into AF thrombotic risk assessment; leaves open whether they improve anticoagulation decisions beyond CHA2DS2-VASc.
Background and aim Atrial fibrillation (AF) is the most common arrhythmia and accounts for one-third of hospitalizations for rhythm disorders in the United States. This increasing burden of AF leads to a higher incidence of stroke. Aim The aim of the study is to assess the risk of thrombogenesis in patients with persistent nonvalvular AF by using transthoracic echocardiogram, transesophageal echocardiogram, and tissue Doppler imaging in relation to the risk of thromboembolism (CHA2DS2-VAS score). Patients and methods Selected 50 patients with persistent AF were included. All patients underwent echocardiography assessment at the echocardiography unit. Results Regarding spontaneous echocardiography contrast, there was a statistically significant difference among the three groups. Regarding left atrial appendage (LAA) thrombus, there was a statistically significant difference among the three groups. Regarding left atial appendage flow velosity (LAAFV), there was an extremely statistically significant difference among the three groups. Regarding left atrial appendage wall velosity (LAAWV) by transthoracic echocardiogram, there was an extremely statistically significant difference among the three groups. Regarding LAAWV by transesophageal echocardiogram, there was an extremely statistically significant difference among the three groups. Conclusion Patients with clinical predictors of high risk included in the CHA2DS2-VASc score were associated with increased incidence of thrombus in the LAA. In patients with nonvalvular AF, the CHA2DS2-VASc score is recommended for assessment of stroke risk. There was a correlation between the development of thromboembolic events and high-risk CHA2DS2-VASc score, as high scores indicate increased thrombogenicity.
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Yousof et al. (2021) studied this question.
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