Clinical Effectiveness of Platelet Concentrates Prepared with or without Acidification of the Plasma

Fresh platelet concentrates prepared with or without acidification of the platelet‐rich plasma were administered to 32 thrombocytopenic patients. A total of 122 transfusions were given including 60 of platelet concentrates from unmodified plasma and 62 of platelets prepared from acidified plasma. In vivo retrieval was calculated by two different and previously used formulas and found to be equivalent for acidified or nonacidified platelet concentrates by either method. Strict adherence to the details of the platelet separation technic is stressed and the possible significance of refrigeration during centrifugation is considered. Non‐modified platelet concentrates are therapeutically effective. They are also economically preferable since they can be obtained as by‐products of ordinary blood banking and do not prejudice the use of the plasma for separation of AHF cryoprecipitates.