Two new urinary metabolites of acetanilide in rats were shown to be the mer-capturic acid derivatives3-[(5-acetamido-2-hydroxyphenyl)thio]-N-acetylalanine and 3-[5-acetamidophenyl)thio]-N-acetylalanine. They accounted for 7–10 and 1–3% of urinary radioactivity, respectively. Their mode of formation may involve an intermediate expoxide.
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Grantham et al. (1974) studied this question.
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