Exercise heart rate gradient: A novel index to predict all-cause mortality
Why the study?
Does the exercise heart rate gradient (EHRG) better predict all-cause mortality compared to heart rate reserve or heart rate recovery alone in adults undergoing maximal cycle cardiopulmonary exercise testing?
Population
1,476 subjects aged between 41 and 79 years who completed a maximal cycle cardiopulmonary exercise test…
Comparison
Exercise heart rate gradient score, a combined… vs Heart rate reserve alone or heart rate recovery…
Design
Cohort
Follow-up
mean 7.3 years
Authors
Discussion
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Member takes
Implication
Should not yet alter CPET risk stratification; leaves open whether EHRG adds incremental value in prospective cohorts.
Structured PICO
Does the exercise heart rate gradient (EHRG) better predict all-cause mortality compared to heart rate reserve or heart rate recovery alone in adults undergoing maximal cycle cardiopulmonary exercise testing?
P
Population
1,476 subjects (937 males) aged between 41 and 79 years who completed a maximal cycle cardiopulmonary exercise test while not using medication with negative chronotropic effects or having an implantable cardiac pacemaker.
I
Intervention
Exercise heart rate gradient (EHRG) score, a combined index of heart rate reserve and heart rate recovery.
C
Comparator
Heart rate reserve alone or heart rate recovery alone (lowest quintiles).
O
Outcome
All-cause mortalityhard clinical
The exercise heart rate gradient (EHRG), which combines heart rate reserve and recovery, is a superior predictor of all-cause mortality compared to either metric alone.
Cite This Study
Duarte et al. (2014) studied this question.