Why the study?
Diagnosis of rare primary liver cancers remains challenging due to low incidence, and the role of locoregional and systemic therapies remains poorly studied.
This review summarizes recent advances in the diagnosis and clinical management of rare primary liver cancers, highlighting that histology remains the gold standard for diagnosis and resection or transplantation are the cornerstones of treatment.
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Diagnosis of rare liver cancers remains challenging; leaves open optimal roles for locoregional and systemic therapies.
fusions, respectively), while the pathogenesis of hepatocholangiocarcinoma remains more complex, as suggested by its histological diversity. Histology is the gold standard for diagnosis, which remains challenging even in an expert centre because of the low incidences of these liver cancers. Resection, when feasible, is the cornerstone of treatment, together with liver transplantation for hepatic haemangioendothelioma. The role of locoregional therapies and systemic treatments remains poorly studied. In this review, we aim to describe the recent advances in terms of diagnosis and clinical management of these rare primary liver cancers.
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Gigante et al. (2020) studied this question.
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