Why the study?
Does mean VO2 response time differ between patients with symptomatic LVSD and controls during exercise, and what are its hemodynamic correlates?
Population
42 patients with symptomatic left ventricular systolic dysfunction and 17 controls.
Comparison
Maximum upright cycle ergometry cardiopulmonary… vs Controls with normal left ventricular ejection…
Design
Cross-sectional
Authors
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Prolonged MRT may signal RV-pulmonary vascular impairment in LVSD; leaves open its utility for risk stratification or therapy guidance.
Does mean VO2 response time differ between patients with symptomatic LVSD and controls during exercise, and what are its hemodynamic correlates?
Delayed oxygen uptake on initiation of exercise in LVSD is closely related to impaired right ventricular-pulmonary vascular function.
Chatterjee et al. (2013) studied this question.
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