Key result
Post-exercise S4 or ST shift occurs in ~97% of angina patients vs. 30% of controls.
Case-Control (n=200)
Answers are grounded in this paper and cite their sources.
One hundred patients with angina and 100 normal subjects, mean age 51 years, had simultaneous phonocardiograms and electrocardiograms at rest and after a double Master's test. A fourth heart sound was present at rest in 43% of the patients and 14% of the normal subjects, and after exercise in 94% of the patients and 29% of the normal subjects. All patients and the normal subject who had a third heart sound at rest had a fourth heart sound at rest, and all who had a third heart sound after exercise had a fourth heart sound after exercise. Fifty-nine per cent of the patients and 4% of the normal subjects had an ST-segment shift ≥1.0 mm, and 67% of the patients and 6% of the normal subjects had an ST-segment shift ≥0.5 mm. After exercise, 97% of the patients and 30% of the normal subjects had a fourth heart sound or an ST-segment shift ≥0.5 mm.
No takes yet. Share an insight, caveat, or question.
Aronow et al. (1971) conducted a case-control in Angina pectoris (n=200). Angina pectoris vs. Normal subjects was evaluated on Presence of a fourth heart sound or an ST-segment shift ≥0.5 mm after exercise. After exercise, 97% of patients with angina pectoris exhibited a fourth heart sound or an ST-segment shift ≥0.5 mm, compared with 30% of normal subjects.
Synapse has enriched 10 related papers. Consider them for comparative context: