Answers are grounded in this paper and cite their sources.
The distribution of VPA has been investigated in several brain areas of the rat, and GABA increases were measured. A biphasic exponential decay was observed for VPA; the slowest decrease was noted in the olfactory bulbs and in the hypothalamus where GAD and GABA-T activities were the highest. The data may be correlated with the prolonged effect of VPA in these areas.
No takes yet. Share an insight, caveat, or question.
Hariton et al. (1984) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: