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December 25, 2024Pharmacological ResearchOpen Access

Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease

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Authors

JWJingyun WuOslo University HospitalISIrene Santos‐GarcíaUniversidad Complutense de MadridIEIván EirizOslo University Hospital

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Wu et al. (2024) studied this question.

synapsesocial.com/papers/6a7038bdac440176ef28def9https://doi.org/10.1016/j.phrs.2024.107557
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neuropathological Classification of Huntingtonʼs Disease1985 · 2,638 citations
  2. 2FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models2019 · 25 citations
  3. 3Neuroprotective effects of fingolimod in mouse models of Parkinson's disease2016 · 117 citations
  4. 4Effect of Myriocin on Plasma Sphingolipid Metabolism and Atherosclerosis in apoE-deficient Mice2004 · 298 citations