Key result
Diffusion- and perfusion-weighted MRI enables early ischemic tissue delineation to guide acute stroke thrombolysis.
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Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) are recently developed yet steadily evolving magnetic resonance techniques. DWI and PWI typically interrogate the microscopic diffusion and microcirculatory perfusion, and they can provide early, highly sensitive, and specific delineation of ischemic tissue. These techniques also can play a role in selecting patients who may benefit from thrombolytic therapy. This article reviews physical, technical, and pathophysiological background material that can be helpful in the acquisition and interpretation of DWI and PWI.
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Özsunar et al. (2000) conducted a review in Acute Ischemic Stroke. Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) was evaluated. Diffusion- and perfusion-weighted MRI provide early, specific delineation of ischemic tissue and can help select patients for thrombolytic therapy in acute ischemic stroke.
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