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Acute inflammation with high ferritin levels, such as in COVID-19, may be associated with acquired long QT and ventricular arrhythmias, warranting ECG screening.
May prompt QTc monitoring in hyperferritinemic inflammation; leaves open whether screening improves outcomes beyond case reports.
We report a case series of 4 patients with transient marked QTc prolongation and ventricular arrhythmias in the setting of inflammation with very high ferritin levels. Three patients were positive for coronavirus disease-2019. In the setting of an acute rise in inflammatory markers, electrocardiography screening for QTc prolongation is warranted. (Level of Difficulty: Beginner.)
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Beer et al. (2021) studied this question.
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