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August 3, 2026Emerging infectious diseasesOpen Access

Evaluation of Detection Methods for Wastewater Surveillance of Antimicrobial-Resistant Bacteria from Healthcare Facilities

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Authors

EWEan WarrenUniversity of UtahJVJames VanDersliceUniversity of UtahLBL. Scott BensonUniversity of Utah

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Implication

Randomized trial evaluates wastewater sampling for antimicrobial resistance monitoring in healthcare facilities, suggesting effective methods for public health tracking.

Key Points

  • To assess the feasibility of wastewater sampling methods for monitoring antimicrobial-resistant bacteria in long-term care facilities.
  • Evaluated composite and passive wastewater sampling methods for carbapenemase gene detection.
  • Conducted over 16 months at a long-term care facility with comparisons to clinical infections.
  • Utilized qPCR and GeneXpert® Carba-R for gene detection.
  • Routine detection of bla KPC in composite samples: 6.4±0.8 log 10 gene copies/ml (100%).
  • Passive samples showed bla VIM detection at 6.6±0.5 log 10 gene copies/g (96%).
  • Sewer biofilm samples contained carbapenemase genes with 100% detection for bla KPC and bla OXA-48-like.

Cite This Study

Warren et al. (2026) studied this question.

synapsesocial.com/papers/6a703fe175942ff7265e48b1https://doi.org/10.3201/eid3213.251490
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Also Consider

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