Population
121 Enterovirus 71 strains isolated from patients with hand, foot and mouth disease in Fukushima, Japan…
Design
Other
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May inform pediatric EV71 surveillance; leaves open whether global transmission drives repeated outbreaks.
Repeated EV71 outbreaks in Japan may be driven by the worldwide transmission of newly introduced genetically divergent strains.
Hosoya et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: