The Relationship Between DHA+Choline Supplementation and the Frequency of Infection-Related Admissions and Antibiotic Use in Children Aged 7–15 Years: A Retrospective Multicenter Cohort Study

Key Points

This study aims to evaluate the impact of DHA and choline supplementation on infection-related outpatient visits and antibiotic use in children aged 7 to 15.
Retrospective observational two-group cohort study
Conducted in 13 pediatric centers with two groups: DHA+choline supplementation group and control group (n=75 each)
Outcome assessed using a 50-item Likert questionnaire and statistical analyses including Mann-Whitney U, Wilcoxon, and Chi-square tests.
Children receiving DHA+choline had fewer infection-related outpatient visits compared to controls
Antibiotic use was lower in the DHA+choline group compared to the untreated group
Statistical analysis indicated significant differences with p-values < 0.05

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Retrospective cohort study evaluates DHA and choline effects on infections and antibiotic use in children, suggesting health benefits.

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Arıca et al. (2026) studied this question.

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