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March 3, 2005Journal of Clinical Investigation

Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells

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Authors

SCS. CindyGarvan Institute of Medical ResearchNHNathan J. HareThe University of SydneyKNKim E. NicholsSt. Jude Children's Research Hospital

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Cite This Study

Cindy et al. (2005) studied this question.

synapsesocial.com/papers/6a7042e62163a0a01bc47979https://doi.org/10.1172/jci23139
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mice deficient in the X‐linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus‐68 and hypo‐gammaglobulinemia2003 · 73 citations
  2. 2Polymorphism of the Interleukin‐10 Gene Is Associated with Susceptibility to Epstein‐Barr Virus Infection1999 · 147 citations
  3. 3Loss of circulating CD27+ memory B cells and CCR4+ T cells occurring in association with elevated EBV loads in XLP patients surviving primary EBV infection2003 · 57 citations
  4. 4Epstein--Barr Virus-Negative Boys With Non-Hodgkin Lymphoma Are Mutated in the Sh2D1A Gene, as Are Patients With X-Linked Lymphoproliferative Disease (XLP)1999 · 108 citations