Population
Human obese visceral adipose tissue, human adipose stromal cells, and murine adipogenesis models
Comparison
Glucocorticoid exposure, LMO3 overexpression… vs Control conditions and murine adipogenesis models
Design
Preclinical
Authors
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LMO3 may link excess glucocorticoids to human visceral adiposity; leaves open its therapeutic targeting pending in vivo studies.
LMO3 is identified as a critical, human-specific regulator of adipogenesis, providing a potential mechanism for visceral fat accumulation in obesity due to excess glucocorticoids.
Lindroos et al. (2013) studied this question.
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