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December 1, 1997EndocrinologyOpen Access

Insulin Stimulates the Phosphorylation and Activity of Farnesyltransferase via the Ras-Mitogen-Activated Protein Kinase Pathway*

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MGMarc L. GoalstoneUniversity of Colorado DenverKCKirstin CarelChildren's Hospital ColoradoJLJ. Wayne LeitnerCedars-Sinai Medical Center

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Goalstone et al. (1997) studied this question.

synapsesocial.com/papers/6a705542f44fa9f079ddf27bhttps://doi.org/10.1210/endo.138.12.5621
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Insulin on Farnesyltransferase Activity in 3T3-L1 Adipocytes1996 · 67 citations
  2. 2p21ras is modified by a farnesyl isoprenoid.1989 · 859 citations
  3. 3Ras Activation by Insulin and Epidermal Growth Factor through Enhanced Exchange of Guanine Nucleotides on p21ras1993 · 173 citations
  4. 4Expression and function of IRS-1 in insulin signal transmission.1992 · 335 citations
  5. 5How MAP Kinases Are Regulated1995 · 1,736 citations