Why the study?
Is the ACTN3 gene variant R577X associated with elite athlete status and human muscle performance?
Population
Humans worldwide
Design
Review
Authors
Discussion
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Member takes
Implication
Supports ACTN3 role in performance variation; leaves open whether genotyping informs athlete selection or training.
Structured PICO
Is the ACTN3 gene variant R577X associated with elite athlete status and human muscle performance?
P
Population
Humans worldwide
I
Intervention
ACTN3 gene variant R577X
O
Outcome
Elite athlete status and normal variation in human muscle strength and sprinting speed
The ACTN3 R577X variant is a key genetic factor associated with elite athletic performance and muscle strength.
Cite This Study
MacArthur et al. (2007) studied this question.