Why the study?
The growing demand for genotyping raises ethical and social issues regarding the usefulness of genotyping healthy individuals and the scientific reliability of direct-to-consumer genetic testing.
This review systematizes laboratory diagnostic methods for studying nucleic acids related to human health and athletic physical qualities, highlighting ethical issues with direct-to-consumer testing.
Genotyping for athletic traits requires ethical safeguards before any clinical use; leaves open rigorous validation in athlete cohorts.
Molecular genetic methods are an integral part of recent medicine. Polymerase chain reaction, Sanger sequencing, next-generation sequencing are widely used in many areas: diagnostics of infectious, inherited, oncological diseases, prenatal screening, study of polymorphisms that increase the risk of developing multifactorial diseases or promoting development physical qualities necessary to achieve success in sports and competitive activity. The growing demand for genotyping raises a number of ethical and social issues affecting the degree of usefulness of genotyping a healthy person and the scientific reliability of the data obtained using direct-to-consumer genetic testing. The review presents and systematizes the laboratory diagnostic methods used today to study nucleic acids that carry important information about human health and physical qualities.
No takes yet. Share an insight, caveat, or question.
Zholinsky et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: