Key result
Exaggerated blood pressure responsiveness to exercise and higher BMI were associated with lower middle cerebral arterial blood flow velocity during exercise in young adults (P < .01).
Why the study?
Is exaggerated blood pressure responsiveness to exercise associated with altered middle cerebral arterial blood flow velocity in young adults?
Cross-Sectional (n=10)
Is exaggerated blood pressure responsiveness to exercise associated with altered middle cerebral arterial blood flow velocity in young adults?
Young adults with an exaggerated blood pressure response to exercise and higher BMI exhibit lower middle cerebral arterial blood flow velocity during exercise, which may increase the risk of cerebral hypoperfusion.
May indicate cerebral hypoperfusion risk during exercise; hypothesis-generating for cerebrovascular outcomes in young adults.
We studied 10 young adults, normotensive at rest, comprising a control group (n = 5) with normal blood pressure responsiveness to exercise and an experimental group exhibiting greater percentage of body fat and body mass index (BMI) than the controls, with exaggerated blood pressure (vasopressor) responsiveness to exercise (EEBPR) (n = 5). Lower absolute and varying oxygen consumption/body weight normalized units of middle cerebral arterial blood flow velocity (MCAV) were found during exercise in the experimental group (P < .01). These findings support the hypothesis that the combination of EEBPR and high BMI is associated with low MCAV that may put such individuals at risk for cerebral hypoperfusion and cognitive deficits.
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Bond et al. (2012) conducted a cross-sectional in Exaggerated blood pressure responsiveness to exercise (n=10). Exaggerated blood pressure responsiveness to exercise (EEBPR) and higher BMI vs. Normal blood pressure responsiveness to exercise was evaluated on Middle cerebral arterial blood flow velocity (MCAV) during exercise (p=< .01). Exaggerated blood pressure responsiveness to exercise and higher BMI were associated with lower middle cerebral arterial blood flow velocity during exercise in young adults (P < .01).
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