Abstract *To whom correspondence should be addressed. 3Present address: Laboratoire de Biologie Moléculaire et Cellulaire, Ecole Normale Supérieure de Lyon, 6 allée d’Italie, 69364 Lyon cedex 07, France, marc.robinson@ens-lyon.fr Summary: RRTree is a user-friendly program for comparing substitution rates between lineages of protein or DNA sequences, relative to an outgroup, through relative rate tests. Genetic diversity is taken into account through use of several sequences, and phylogenetic relations are integrated by topological weighting. Availability: The ANSI C source code of RRTree, and compiled versions for Macintosh, MS-DOS/Windows, SUN Solaris, and CGI, are freely available at http://pbil.univ-lyon1.fr/software/rrtree.html Contact: marc.robinson@ens-lyon.fr
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Robinson‐Rechavi et al. (2000) studied this question.