Reaction of Anthranilonitrile with Some Active Methylene Reagents: Synthesis of Some New Quinoline and Quinazoline Derivatives

Anthranilonitrile (1) reacts with ethyl cyanoacetate and its dimer, malononitrile, cyanothioacetamide and N‐arylidene cyanoacetohydrazides 12a–c to afford pyrano[2,3‐b]quinoline 5, cyanomethyl‐quinazoline 10, pyrazolo[2,3‐a]quinazoline 12 and triazolo[4,3‐a]‐quinoline derivatives 16a–c, respectively. Structures and conceivable mechanisms are discussed.