Key result
Obese school-aged children had lower gut microbiota α-diversity, fewer dominant probiotics, and more genera linked to metabolic disorders and inflammation compared to average-weight children.
Why the study?
Is obesity associated with altered diversity and genus of gut microbiota in school-aged children?
Is obesity associated with altered diversity and genus of gut microbiota in school-aged children?
Obesity in school-aged children is associated with an unfavorable gut microbiota profile, characterized by lower diversity and fewer probiotics.
Highlights potential microbiota role in pediatric obesity; leaves open whether diversity restoration improves outcomes.
Compared with children with average weight, obese children had lower α diversity of gut microbiota and lower relative abundance of dominant probiotics but had a higher relative lot of genus associated with metabolic disorders, inflammation promotion, and metabolism rate reduction.
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Jiang et al. (2022) studied this question. Obese school-aged children had lower gut microbiota α-diversity, fewer dominant probiotics, and more genera linked to metabolic disorders and inflammation compared to average-weight children.
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