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Background: The number of clinical applications of different Platelet-Rich Fibrin (PRF) membranes has increased in regenerative medicine including regenerative dentistry. Intact platelets, leukocytes and stem cells of PRF play a crucial role in the local bone augmentation releasing cytokines and growth factors. An integral part of the post-surgical management is the application of mouthwashes, especially chlorhexidine digluconate, which is recommended in order to prevent postoperative infections. In some cases, it is possible that there is contact between the mouthwash and PRF membrane. Therefore, the impact of mouthwashes on cell viability of folded F-PRF was tested.
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Csonge et al. (2022) studied this question.
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