Effect of Pre-Incisional and Mesosalpinx Infiltration of Local Anaesthesia for Post-Operative Analgesia in Bilateral Abdominal Tubectomies- A Randomised Placebo-Controlled Study

BACKGROUND aim of the study is to evaluate the effectiveness of subcutaneous pre-incisional and mesosalpinx infiltration of 0.5% in post-operative pain relief. AND METHODS is a randomised placebo-controlled double-blind study conducted at Bangalore Medical College and Research Institute on 50 patients scheduled for elective tubal ligation by minilaparotomy under general anaesthesia from April to October 2014. were randomised into 2 groups of 25 each by computer generated random list. Group A patients received 0.5% 10 cc pre-incisional subcutaneous and 5 cc in the mesosalpinx, while Group B patients received normal saline . In this study, the intensity of post-operative pain was assessed using Verbal Rating Scale (VRS). Data collection was using questionnaire and collected data was analysed by Student’s t-test, Chi-square and Fisher Exact test using SPSS and descriptive statistical programme, p value < 0.01 was considered significant. 50 patients were studied in two groups. Age and weight of the patients were comparable between 2 groups. Pain score in room 2, 4, 6, 8, 10 hours post-surgery were significantly less in bupivacaine group (p < 0.005). Time for rescue is 3.92 ± 1.07 hrs. in Group A compared to 1.32 ± 0.54 in Group B with p < 0.01. -incisional and mesosalpinx infiltration of 0.5% bupivacaine in abdominal tubectomies by minilaparotomy led to significant of post-operative pain with prolonged period for rescue analgesia.