Key result
Thick left ventricular hypertrophy was associated with the greatest odds of ischemic stroke compared to normal geometry (OR 2.143; 95% CI 1.329-3.456), followed by indeterminate hypertrophy.
Why the study?
Is a novel 4-tiered classification of left ventricular hypertrophy associated with ischemic stroke prevalence in the general population?
Cross-Sectional (n=11,037)
Is a novel 4-tiered classification of left ventricular hypertrophy associated with ischemic stroke prevalence in the general population?
Odds Ratio: 2.143 (95% CI 1.329–3.456)
p-value: p=<.05
A novel 4-tiered classification of left ventricular hypertrophy identifies thick and indeterminate hypertrophy as carrying significantly higher odds of ischemic stroke in the general population.
LV geometry may refine stroke risk stratification in observational data; hypothesis-generating and requires prospective validation before practice change.
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Wang et al. (2018) conducted a cross-sectional in Left ventricular hypertrophy (n=11,037). Thick left ventricular hypertrophy vs. Normal LV geometry was evaluated on Ischemic stroke (OR 2.143, 95% CI 1.329-3.456, p=<.05). Thick left ventricular hypertrophy was associated with the greatest odds of ischemic stroke compared to normal geometry (OR 2.143; 95% CI 1.329-3.456), followed by indeterminate hypertrophy.
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