Key result
Cyanotic and acyanotic congenital heart disease in infants were associated with pathological thrombelastography parameters in 41% (P=0.003) and 17% (P=0.01) of patients, respectively.
Why the study?
Does cyanotic or acyanotic congenital heart disease impair whole blood coagulation measured by modified thrombelastography in infants?
Observational (n=51)
Does cyanotic or acyanotic congenital heart disease impair whole blood coagulation measured by modified thrombelastography in infants?
p-value: p=0.003
Cyanosis and polycythemia in infants with congenital heart disease significantly impair hemostasis as measured by modified thrombelastography.
No takes yet. Share an insight, caveat, or question.
Should not yet change perioperative management; hypothesis-generating for TEG abnormalities in infant congenital heart disease.
Osthaus et al. (2008) conducted an observational in Congenital heart disease (n=51). Cyanotic and acyanotic congenital heart disease vs. Normal patients without CHD was evaluated on Pathological TEM parameters (p=0.003). Cyanotic and acyanotic congenital heart disease in infants were associated with pathological thrombelastography parameters in 41% (P=0.003) and 17% (P=0.01) of patients, respectively.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: