Case Report (n=1)
Myocardial infarction can be complicated by left ventricular thrombosis and subsequent coronary embolism even with timely PCI and early reperfusion.
The thrombus formation in the left ventricle (LV) cavity is a frequent complication of myocardial infarction (MI) as well as a risk factor for peripheral arterial embolism. Probability of intraventricular thrombus depends on MI location and its therapy. A case of coronary embolism in a patient with anterior MI and thrombus in the LV aneurysm is considered in details. Successful percutaneous coronary intervention (PCI) in the first 90 minutes after admission was performed. Decision to appoint a three-component antithrombotic therapy (acetylsalicylic acid, clopidogrel, warfarin) was made on the 4th day of disease onset taking into account the combination of MI, stent placement in the anterior interventricular artery and the presence of left ventricular aneurysm with parietal thrombus. Recurrence of MI developed on the 9th day of disease onset. Aspiration thromboembolectomy was performed taking into account thrombosis of two coronary arteries. Warfarin therapy was discontinued in connection with subsequent clot lysis and development of not intensive nosebleed. Subsequent MI course was uneventful. In conclusion, even in spite of the timely achievement of PCI and early reperfusion, MI course can be complicated by thrombosis of the left ventricle and subsequent development of thromboembolic complications.
No takes yet. Share an insight, caveat, or question.
Salakhova et al. (2011) conducted a case report in Anterior myocardial infarction with left ventricular aneurysm and thrombus (n=1). Percutaneous coronary intervention and antithrombotic therapy was evaluated.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More from Rational Pharmacotherapy in Cardiology