Why the study?
Does the presence of atrial septal aneurysm alter the location of brain infarcts compared to other stroke etiologies in patients with ischemic stroke?
Does the presence of atrial septal aneurysm alter the location of brain infarcts compared to other stroke etiologies in patients with ischemic stroke?
In patients with ischemic stroke, the presence of an atrial septal aneurysm is not associated with a higher frequency of vertebrobasilar infarcts compared to other stroke etiologies.
ASA does not raise vertebrobasilar infarct prevalence in ischemic stroke; leaves open infarct location's diagnostic value.
It has been suggested that, in patients with atrial septal aneurysm (ASA), brain infarcts occur more frequently in the vertebrobasilar territory. The aim of our study was to compare the location of infarcts between (1) 26 patients with an ASA and no other potential cause of stroke; (2) 76 patients with presumed cardioembolic stroke and no ASA, and (3) 64 patients with large-vessel atherosclerosis (LVA) and no ASA. Infarcts were less likely to be cortical (p = 0.005) in the ASA group than in the LVA group. The location of infarcts did not significantly differ between ASA and cardioembolic groups. The prevalence of vertebrobasilar infarcts did not differ between groups. This study did not support the hypothesis that, in patients with ASA, brain infarcts occur more frequently in the vertebrobasilar territory.
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Lucas et al. (1994) studied this question.
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