Bromine‐lithium exchange in 1,1‐dibromo‐3‐(trimethylsilyl‐oxy)alkanes 4 and 6 affords the carbenoids 8 and 14 , which have been added to ketones, aldehydes, arylboronates, and silylating agents. Diastereoselectivity in the generation and trapping of the carbenoids ranged between 70 – 90% for 8 and >90% for 14 .
No takes yet. Share an insight, caveat, or question.
Hoffmann et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: