Answers are grounded in this paper and cite their sources.
A Pd-catalyzed ortho-acetoxylation of masked benzyl alcohols to synthesize various 2-hydroxyalkylphenol derivatives is reported. The 2,6-dimethoxyl benzaldoxime proved to be an efficient exo-type directing group for arene (sp(2)) C-H functionalization. Two strategies were demonstrated to remove the directing group through N-O and C-O bond cleavages. A high catalyst turnover (>1000) was obtained to illustrate the practicality of this method.
No takes yet. Share an insight, caveat, or question.
Ren et al. (2015) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: