Why the study?
Does P2Y12 antagonism reduce physiological thromboxane levels in mice and humans?
Does P2Y12 antagonism reduce physiological thromboxane levels in mice and humans?
P2Y12 antagonism alone can decrease physiological thromboxane levels, suggesting potential new treatment regimens for patients allergic or non-responsive to aspirin.
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P2Y12 antagonism may lower thromboxane levels; hypothesis-generating for regimens in aspirin-allergic patients, pending trials.
Bhavaraju et al. (2010) studied this question.
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