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August 1, 2001Molecular Biology of the CellOpen Access

Polyubiquitination Is Required for US11-dependent Movement of MHC Class I Heavy Chain from Endoplasmic Reticulum into Cytosol

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Authors

CSCaroline E. ShamuHarvard UniversityDFDennis FliermanLeiden University Medical Center
Hidde L. Ploegh
Hidde L. PloeghBroad Institute

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Cite This Study

Shamu et al. (2001) studied this question.

synapsesocial.com/papers/6a707d3cf44fa9f079de23c6https://doi.org/10.1091/mbc.12.8.2546
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Also Consider

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  1. 1The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products1999 · 88 citations
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  3. 3ER Degradation of a Misfolded Luminal Protein by the Cytosolic Ubiquitin-Proteasome Pathway1996 · 714 citations
  4. 4The Pathway of Us11-Dependent Degradation of Mhc Class I Heavy Chains Involves a Ubiquitin-Conjugated Intermediate1999 · 151 citations
  5. 5Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast1993 · 212 citations