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February 8, 2018Scientific ReportsOpen Access

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres

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Authors

AGAndrew S. GilderJackson Memorial HospitalLNLetizia NataliKedrion (Italy)DDDanielle M. Van DykUniversity of California, San Diego

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Gilder et al. (2018) studied this question.

synapsesocial.com/papers/6a708085439bab0cabc3320ahttps://doi.org/10.1038/s41598-018-21358-1
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Also Consider

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  1. 1A Urokinase Receptor–Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma2014 · 59 citations
  2. 2Reversibility of Epithelial-Mesenchymal Transition (EMT) Induced in Breast Cancer Cells by Activation of Urokinase Receptor-dependent Cell Signaling2009 · 176 citations
  3. 3Transcriptional Profiles of CD133+ and CD133− Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin2010 · 273 citations