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Of 15 patients with Turner's syndrome studied for renal anomalies by intravenous pyelogram, 11 had demonstrable abnormalities ; three had horseshoe kidney. None had evidence of impaired renal func tion. Four reported previous urinary tract infections. Similarities among the positional and structural abnormalities of the kidneys suggested a continuum of morphologic changes, with a possible re lationship of such changes to impaired positional information pro gramming by the developing abnormal gonad during embryogenesis.
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Matthies et al. (1971) studied this question.
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