The Application of Combined Preparations With Constant Doses of Antihypertensive Drugs as the Initial Tactics of Treatment at High Blood Pressure Level: Proven Facts and Expert’s Opinion

In this article the current problems of the use of combined antihypertensive drugs in the implementation of «tactics one tablet» in a wide range of patients with arterial hypertension are discussed. The results of the discussion of such a problem by experts, as well as the main provisions of the agreement document, are given, devoted to approaches to the implementation of tactics of wider use of combined antihypertensive drugs containing 2 or more antihypertensive drugs in one tablet. Both the advantages and disadvantages of «tactics one tablet « are considered. The results of clinical studies are discussed, which confirm the validity of the use of the combined antihypertensive therapy as an initial tactic of treatment of the majority of patients with arterial hypertension. The results of the assessment of pharmacoeconomic indicators are given when using combined antihypertensive therapy.