Voltammetric Determination of Rutin Using a Carbon Composite Electrode Modified with Copper(II)-Resin

The preparation and electrochemical characterization of a carbon composite electrode modified with copper(II)-resin as well as its behavior toward rutin were investigated using cyclic and linear sweep voltammetry. The best voltammetric response was observed for a composite composition of 20% (m/m) copper(II)-resin, 0.10 mol L−1 KNO3/10−6 mol L−1 HNO3 solution (pH 6.0) as the supporting electrolyte, and a scan rate of 50 mVs−1. A linear voltammetric response for rutin was obtained in the concentration range from 9.90 × 10−7 to 8.07 × 10−6 mol L−1, with a detection limit of 2.65 × 10−8 mol L−1. The proposed electrode was useful for the quality control and routine analysis of rutin in pharmaceutical formulations.