The Escherichia coli AcrB efflux pump is a resistance-nodulation-division (RND) pump that recognizes many unrelated compounds ([9][1], [10][2]). AcrB forms a complex with AcrA and TolC and is the single most important contributor to multidrug resistance in E. coli . Crystallographic models suggest
No takes yet. Share an insight, caveat, or question.
Wehmeier et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: