Why the study?
Cardiovascular computational fluid dynamics is increasingly used to predict hemodynamic changes around aortic dissection treatment, but the effects of flow boundary conditions on patient-specific aortic hemodynamics needed investigation.
How do different flow boundary conditions affect patient-specific aortic hemodynamics in computational fluid dynamics models of aortic dissection?
How do different flow boundary conditions affect patient-specific aortic hemodynamics in computational fluid dynamics models of aortic dissection?
Incorporating an auxiliary inflow structure at the aortic valve in computational fluid dynamics models significantly improves the physiological authenticity of ascending aorta hemodynamics simulations.
Different BCs may alter CFD hemodynamics in type A AD models; leaves open optimal protocols before clinical use.
Cardiovascular computational fluid dynamics (CFD) based on patient-specific modeling is increasingly used to predict changes in hemodynamic parameters before or after surgery/interventional treatment for aortic dissection (AD). This study investigated the effects of flow boundary conditions (BCs) on patient-specific aortic hemodynamics. We compared the changes in hemodynamic parameters in a type A dissection model and normal aortic model under different BCs: inflow from the auxiliary and truncated structures at aortic valve, pressure control and Windkessel model outflow conditions, and steady and unsteady inflow conditions. The auxiliary entrance remarkably enhanced the physiological authenticity of numerical simulations of flow in the ascending aortic cavity. Thus, the auxiliary entrance can well reproduce the injection flow from the aortic valve. In addition, simulations of the aortic model reconstructed with an auxiliary inflow structure and pressure control and the Windkessel model outflow conditions exhibited highly similar flow patterns and wall shear stress distribution in the ascending aorta under steady and unsteady inflow conditions. Therefore, the inflow structure at the valve plays a crucial role in the hemodynamics of the aorta. Under limited time and calculation cost, the steady-state study with an auxiliary inflow valve can reasonably reflect the blood flow state in the ascending aorta and aortic arch. With reasonable BC settings, cardiovascular CFD based on patient-specific AD models can aid physicians in noninvasive and rapid diagnosis.
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Chi et al. (2022) studied this question.
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