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Review outlines the chemistry, measurement, and clinical utility of glycated proteins in diabetes management.
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The recognition that nonenzymatic glycation, wherein free sugar condenses with certain reactive protein amino groups, is increased in hyperglycemic states has led to improved means for assessing diabetic control through the measurement of concentrations of glycated proteins in the circulation. This article reviews the chemistry, methods for measurement, and clinical relevance of circulating glycated proteins in the management of diabetes.
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Cohen et al. (1999) conducted a review in diabetes. Measurement of circulating glycated proteins was evaluated. This review summarizes the chemistry, measurement methods, and clinical relevance of circulating glycated proteins for assessing diabetic control.
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