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July 1, 1967ThoraxOpen Access

The mechanism of hypoxaemia after laparotomy

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Population

18 patients undergoing upper laparotomies

Comparison

Upper laparotomy vs Pre-operative baseline

Design

Cohort

Follow-up

First post-operative day and later in the post-operative…

Authors

JGJ GeorgUniversity of CopenhagenIHIb HornumUniversity of CopenhagenKMKresten MellemgaardRegional Hospital Central Jutland

Discussion

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Implication

Emphasizes ventilation-perfusion mismatch over shunting for post-laparotomy hypoxaemia management; supports mechanistic studies but leaves confirmation to prospective trials.

Structured PICO

P
Population
18 patients undergoing upper laparotomies
I
Intervention
Upper laparotomy
C
Comparator
Pre-operative baseline
O
Outcome
Alveolo-arterial oxygen difference and right-to-left shuntsurrogate

Post-operative hypoxaemia following upper laparotomy is primarily driven by ventilation-perfusion mismatch rather than veno-arterial shunting.

Cite This Study

Georg et al. (1967) studied this question.

synapsesocial.com/papers/6a7090e5febe604dd709567ehttps://doi.org/10.1136/thx.22.4.382
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Partial Gastrectomy on Pulmonary Physiology1964 · 56 citations
  2. 2The Alveolar‐Arterial Oxygen Difference: Its Size and Components in Normal Man1966 · 240 citations