Synthesis and Characterization of Biologically Active Organosilicon(IV) Complexes with Schiff Bases Derived from o-aminothiophenol

The synthesis and structural features of some organosilicon(IV) complexes with Schiff bases derived by condensing Substituted benzaldehyde with o-aminothiophenol have been discussed. The newly synthesized compounds have been characterized by elemental analyses, IR, 1H, 13C, and 29Si NMR spectral studies. With the help of spectral studies, penta, and hexacoordinated environments around the central silicon atoms in the 1:1 and 1:2 complexes, respectively, have been proposed. Some have been tested for the growth inhibitory activity against some bacterial and yeast strains in vitro. The antimicrobial studies revealed that the Schiff bases and some of their metal complexes possess more healing activity.