Nonselective vasodilators like dipyridamole should be used with caution in patients with pulmonary hypertension and a D-shaped left ventricle due to the risk of precipitating atrial arrhythmias.
May signal arrhythmia risk with dipyridamole in pulmonary hypertension; hypothesis-generating and should not yet alter practice.
Pulmonary hypertension significantly changes biventricular anatomy and physiology, frequently evolving to clinical deterioration and right ventricular failure. The case of a woman developing atrial arrhythmias complicating dipyridamole stress in concomitance with scintigraphic "D-shaped" left ventricle is briefly reported. Although rare, our finding may suggest that nonselective vasodilators should be used with caution in this clinical setting.
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Ferrando‐Castagnetto et al. (2016) studied this question.
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